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Structural Insights into PROTAC-Mediated Degradation of Bcl-xL.
Chung, Chun-Wa; Dai, Han; Fernandez, Esther; Tinworth, Christopher P; Churcher, Ian; Cryan, Jenni; Denyer, Jane; Harling, John D; Konopacka, Agnieszka; Queisser, Markus A; Tame, Christopher J; Watt, Gillian; Jiang, Fan; Qian, Dongming; Benowitz, Andrew B.
Afiliação
  • Chung CW; Protein, Cellular & Structural Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
  • Dai H; Protein Degradation Group, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States.
  • Fernandez E; Protein Degradation Group, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
  • Tinworth CP; Protein Degradation Group, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
  • Churcher I; Protein Degradation Group, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
  • Cryan J; Protein Degradation Group, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
  • Denyer J; Protein Degradation Group, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
  • Harling JD; Protein Degradation Group, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
  • Konopacka A; Protein Degradation Group, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
  • Queisser MA; Protein Degradation Group, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
  • Tame CJ; Protein Degradation Group, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
  • Watt G; Protein Degradation Group, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
  • Jiang F; Viva Biotech, Ltd., 334 Aidisheng Rd., Zhangjiang High-tech Park, Shanghai 201203, China.
  • Qian D; Viva Biotech, Ltd., 334 Aidisheng Rd., Zhangjiang High-tech Park, Shanghai 201203, China.
  • Benowitz AB; Protein Degradation Group, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom.
ACS Chem Biol ; 15(9): 2316-2323, 2020 09 18.
Article em En | MEDLINE | ID: mdl-32697072
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Benzotiazóis / Proteína Supressora de Tumor Von Hippel-Lindau / Proteína bcl-X / Proteólise / Isoquinolinas Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Benzotiazóis / Proteína Supressora de Tumor Von Hippel-Lindau / Proteína bcl-X / Proteólise / Isoquinolinas Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article