The Hippo in the room: Targeting the Hippo signalling pathway for osteosarcoma therapies.

Rothzerg, Emel; Ingley, Evan; Mullin, Benjamin; Xue, Wei; Wood, David; Xu, Jiake

Rothzerg, Emel; Ingley, Evan; Mullin, Benjamin; Xue, Wei; Wood, David; Xu, Jiake.

Afiliação

Rothzerg E; School of Biomedical Sciences, The University of Western Australia, Perth, Western Australia, Australia.
Ingley E; Perron Institute for Neurological and Translational Science, QEII Medical Centre, Nedlands, Western Australia, Australia.
Mullin B; Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands, Western Australia, Australia.
Xue W; College of Science, Health, Engineering and Education, Murdoch University, Murdoch, Western Australia, Australia.
Wood D; School of Biomedical Sciences, The University of Western Australia, Perth, Western Australia, Australia.
Xu J; Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.

J Cell Physiol ; 236(3): 1606-1615, 2021 03.

Article em En | MEDLINE | ID: mdl-32697358

Assuntos

Osteossarcoma/enzimologia; Osteossarcoma/terapia; Proteínas Serina-Treonina Quinases/metabolismo; Transdução de Sinais; Animais; Modelos Biológicos; Terapia de Alvo Molecular; Osteossarcoma/patologia

Palavras-chave

Hippo signalling pathway; osteosarcoma; sarcoma; small molecule inhibitor; targeted therapy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Osteossarcoma / Proteínas Serina-Treonina Quinases Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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