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Trans-unsaturated fatty acid activates NLRP3 inflammasome in macrophages and exacerbates intestinal inflammation in mice.
Higashimura, Yasuki; Tanaka, Yumiko; Takagi, Tomohisa; Uchiyama, Kazuhiko; Mizushima, Katsura; Niki, Etsuo; Naito, Yuji.
Afiliação
  • Higashimura Y; Department of Food Science, Ishikawa Prefectural University, Nonoichi, Ishikawa, 921-8836, Japan; Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Kyoto, 602-8566, Japan. Electronic address: yasuki@ishikawa-pu.ac.jp.
  • Tanaka Y; Department of Food Science, Ishikawa Prefectural University, Nonoichi, Ishikawa, 921-8836, Japan.
  • Takagi T; Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Kyoto, 602-8566, Japan.
  • Uchiyama K; Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Kyoto, 602-8566, Japan.
  • Mizushima K; Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Kyoto, 602-8566, Japan.
  • Niki E; Research Center for Advanced Science and Technology, The University of Tokyo, Meguro, Tokyo, 153-0041, Japan.
  • Naito Y; Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Kyoto, 602-8566, Japan.
Biochem Biophys Res Commun ; 529(2): 243-250, 2020 08 20.
Article em En | MEDLINE | ID: mdl-32703418
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colite / Ácidos Graxos trans / Inflamassomos / Proteína 3 que Contém Domínio de Pirina da Família NLR / Macrófagos Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colite / Ácidos Graxos trans / Inflamassomos / Proteína 3 que Contém Domínio de Pirina da Família NLR / Macrófagos Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article