Integration of CRISPR-engineering and hiPSC-based models of psychiatric genomics.

Matos, Marliette R; Ho, Seok-Man; Schrode, Nadine; Brennand, Kristen J

Matos, Marliette R; Ho, Seok-Man; Schrode, Nadine; Brennand, Kristen J.

Afiliação

Matos MR; Graduate School of Biomedical Science, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States of America.
Ho SM; Graduate School of Biomedical Science, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States of America; Department of Stem Cell and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States of America.
Schrode N; Department of Genetics and Genomics, Pamela Sklar Division of Psychiatric Genomics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States of America; Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States of
Brennand KJ; Graduate School of Biomedical Science, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States of America; Department of Stem Cell and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States of America; Department of Genetics and Genomics,

Mol Cell Neurosci ; 107: 103532, 2020 09.

Article em En | MEDLINE | ID: mdl-32712198

Assuntos

Encefalopatias/genética; Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas/genética; Células-Tronco Pluripotentes Induzidas/metabolismo; Transtornos Mentais/genética; Animais; Edição de Genes/métodos; Humanos; Neurônios/metabolismo

Palavras-chave

CRISPR; Human induced pluripotent stem cell; Psychiatric genetics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encefalopatias / Células-Tronco Pluripotentes Induzidas / Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas / Transtornos Mentais Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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