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Occult Hepatitis B Virus Infection in Immunized Infants Born to Untreated and Tenofovir-Treated Highly Viremic Mothers.
Hsu, Hong-Yuan; Chen, Huey-Ling; Wu, Jia-Feng; Ni, Yen-Hsuan; Chang, Kai-Chi; Chiang, Cheng-Lun; Lee, Chien-Nan; Zhao, Lu-Lu; Lai, Ming-Wei; Mu, Shu-Chi; Wen, Wan-Hsin; Lin, Lung-Huang; Chang, Mei-Hwei.
Afiliação
  • Hsu HY; Department of Pediatrics, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan; Department and Graduate Institute of Medical Education and Bioethics, National Taiwan University College of Medicine, Taipei, Taiwan.
  • Chen HL; Department of Pediatrics, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan; Department and Graduate Institute of Medical Education and Bioethics, National Taiwan University College of Medicine, Taipei, Taiwan.
  • Wu JF; Department of Pediatrics, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan.
  • Ni YH; Department of Pediatrics, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan.
  • Chang KC; Department of Pediatrics, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan.
  • Chiang CL; Department of Pediatrics, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan; Department and Graduate Institute of Medical Education and Bioethics, National Taiwan University College of Medicine, Taipei, Taiwan.
  • Lee CN; Department of Obstetrics and Gynecology, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan.
  • Zhao LL; Department of Pediatrics, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan.
  • Lai MW; Division of Pediatric Gastroenterology, Department of Pediatrics, Liver Research Center, Chang Gung Memorial Hospital, Linkou Branch, Taiwan.
  • Mu SC; Department of Pediatrics, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
  • Wen WH; Department of Pediatrics, Cardinal Tien Hospital, New Taipei City, Taiwan.
  • Lin LH; Department of Pediatrics, Cathay General Hospital, Taipei, Taiwan.
  • Chang MH; Department of Pediatrics, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan. Electronic address: changmh@ntu.edu.tw.
Clin Gastroenterol Hepatol ; 19(7): 1494-1496, 2021 07.
Article em En | MEDLINE | ID: mdl-32712392
ABSTRACT
Tenofovir disoproxil fumurate (TDF) therapy during late pregnancy in highly viremic mothers can reduce residual overt hepatitis B virus (HBV) infections of their infants that occur despite immunoprophylaxis.1,2 Occult HBV infection (OBI) has been defined as the presence of HBV DNA in liver or sera in subjects seronegative for hepatitis B surface antigen (HBsAg).3 OBI has been found in varying proportions of immunized infants born to HBsAg-positive mothers.4-6 We aimed to investigate the impact of maternal TDF therapy during pregnancy on vertically acquired OBI.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Hepatite B / Hepatite B Limite: Female / Humans / Infant / Pregnancy Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Hepatite B / Hepatite B Limite: Female / Humans / Infant / Pregnancy Idioma: En Ano de publicação: 2021 Tipo de documento: Article