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Cell-cycle-dependent phosphorylation of RRM1 ensures efficient DNA replication and regulates cancer vulnerability to ATR inhibition.
Shu, Zhen; Li, Zhen; Huang, Huanhuan; Chen, Yan; Fan, Jun; Yu, Li; Wu, Zhihui; Tian, Ling; Qi, Qi; Peng, Shuang; Wei, Changyong; Xie, Zhongqiu; Li, Xiaobo; Feng, Qi; Sheng, Hao; Li, Guangqiang; Wei, Dongping; Shan, Changliang; Chen, Guo.
Afiliação
  • Shu Z; Department of Medical Biochemistry and Molecular Biology, School of Medicine, Jinan University, Guangzhou, 510632, China.
  • Li Z; Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA, 30322, USA.
  • Huang H; Department of Medical Biochemistry and Molecular Biology, School of Medicine, Jinan University, Guangzhou, 510632, China.
  • Chen Y; Biomedical Translational Research Institute, Jinan University, Guangzhou, 510632, China.
  • Fan J; Department of Oncology, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, China.
  • Yu L; Department of Medical Biochemistry and Molecular Biology, School of Medicine, Jinan University, Guangzhou, 510632, China.
  • Wu Z; Department of Medical Biochemistry and Molecular Biology, School of Medicine, Jinan University, Guangzhou, 510632, China.
  • Tian L; Department of Medical Biochemistry and Molecular Biology, School of Medicine, Jinan University, Guangzhou, 510632, China.
  • Qi Q; Department of Medical Biochemistry and Molecular Biology, School of Medicine, Jinan University, Guangzhou, 510632, China.
  • Peng S; Department of Medical Biochemistry and Molecular Biology, School of Medicine, Jinan University, Guangzhou, 510632, China.
  • Wei C; Department of Pathophysiology and Pharmacology, School of Medicine, Jinan University, Guangzhou, 510632, China.
  • Xie Z; Department of Pathophysiology and Pharmacology, School of Medicine, Jinan University, Guangzhou, 510632, China.
  • Li X; Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA, 30322, USA.
  • Feng Q; Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA, 30322, USA.
  • Sheng H; Key Laboratory of Immune Microenvironment and Disease of the Ministry of Education, Tianjin Medical University, Tianjin, 300070, China.
  • Li G; Biomedical Translational Research Institute, Jinan University, Guangzhou, 510632, China.
  • Wei D; Biomedical Translational Research Institute, Jinan University, Guangzhou, 510632, China.
  • Shan C; Biomedical Translational Research Institute, Jinan University, Guangzhou, 510632, China.
  • Chen G; Department of Oncology, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, China.
Oncogene ; 39(35): 5721-5733, 2020 08.
Article em En | MEDLINE | ID: mdl-32712628

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ribonucleosídeo Difosfato Redutase / Replicação do DNA / Proteínas Mutadas de Ataxia Telangiectasia Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ribonucleosídeo Difosfato Redutase / Replicação do DNA / Proteínas Mutadas de Ataxia Telangiectasia Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article