Rtpca: an R package for differential thermal proximity coaggregation analysis.

ABSTRACT

SUMMARY: Rtpca is an R package implementing methods for inferring protein-protein interactions (PPIs) based on thermal proteome profiling experiments of a single condition or in a differential setting via an approach called thermal proximity coaggregation. It offers user-friendly tools to explore datasets for their PPI predictive performance and easily integrates with available R packages. AVAILABILITY AND IMPLEMENTATION Rtpca is available from Bioconductor (https//bioconductor.org/packages/Rtpca). SUPPLEMENTARY INFORMATION Supplementary data are available at Bioinformatics online.