[Low grade glioma with MYBL1 alteration: Case report of an uncommon pediatric neoplasm]. / Gliome de bas grade avec altération de MYBL1 : observation d'une nouvelle entité tumorale pédiatrique.
Ann Pathol
; 41(1): 129-133, 2021 Feb.
Article
em Fr
| MEDLINE
| ID: mdl-32732147
ABSTRACT
Diffuse gliomas with MYB or MYBL1 alterations are rare tumours mostly affecting children or young adults with long-term epilepsy. This category of glioma includes two morphological subtypes. The angiocentric subtype is characterized by an angiocentric pattern of growth and a frequent MYBQKI fusion. The isomorphic subtype corresponds to a highly differentiated astrocytic glioma with low cellularity, low proliferation and no specific microscopic features. The diagnosis is based on the imaging, demonstrating a supratentorial tumor, associated with the confirmation of a MYB or MYBL1 rearrangement. Here, we report the case of a 7-year-old child who presented a right frontal brain lesion corresponding to an isomorphic diffuse glioma with MYBL1 alteration.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Astrocitoma
/
Neoplasias Encefálicas
/
Neoplasias Supratentoriais
/
Glioma
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Child
/
Humans
Idioma:
Fr
Ano de publicação:
2021
Tipo de documento:
Article