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Weekly COVID-19 testing with household quarantine and contact tracing is feasible and would probably end the epidemic.
Peto, Julian; Carpenter, James; Smith, George Davey; Duffy, Stephen; Houlston, Richard; Hunter, David J; McPherson, Klim; Pearce, Neil; Romer, Paul; Sasieni, Peter; Turnbull, Clare.
Afiliação
  • Peto J; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.
  • Carpenter J; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.
  • Smith GD; Bristol Population Health Science Institute, Bristol University, Bristol, UK.
  • Duffy S; Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, UK.
  • Houlston R; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
  • Hunter DJ; Nuffield Department of Population Health, Oxford University, Oxford, UK.
  • McPherson K; New College, Oxford University, Oxford, UK.
  • Pearce N; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.
  • Romer P; Stern School of Business, New York University, New York, USA.
  • Sasieni P; School of Cancer and Pharmaceutical Sciences, King's College London, London, UK.
  • Turnbull C; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
R Soc Open Sci ; 7(6): 200915, 2020 Jun.
Article em En | MEDLINE | ID: mdl-32742705
ABSTRACT
The COVID-19 epidemic can probably be ended and normal life restored, perhaps quite quickly, by weekly SARS-CoV-2 RNA testing together with household quarantine and systematic contact tracing. Isolated outbreaks could then be contained by contact tracing, supplemented if necessary by temporary local reintroduction of population testing or lockdown. Leading public health experts have recommended that this should be tried in a demonstration project in which a medium-sized city introduces weekly testing and lifts lockdown completely. The idea was not considered by the groups whose predictions have guided UK policy, so we have examined the statistical case for such a study. The combination of regular testing with strict household quarantine, which was not analysed in their models, has remarkable power to reduce transmission to the community from other household members as well as providing earlier diagnosis and facilitating rapid contact tracing.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article