Lactoferrin is a dynamic protein in human melioidosis and is a TLR4-dependent driver of TNF-&#945; release in Burkholderia thailandensis infection in vitro.

Wright, Shelton W; Lovelace-Macon, Lara; Ducken, Deirdre; Tandhavanant, Sarunporn; Teparrukkul, Prapit; Hantrakun, Viriya; Limmathurotsakul, Direk; Chantratita, Narisara; West, T Eoin

Lactoferrin is a dynamic protein in human melioidosis and is a TLR4-dependent driver of TNF-α release in Burkholderia thailandensis infection in vitro.

Wright, Shelton W; Lovelace-Macon, Lara; Ducken, Deirdre; Tandhavanant, Sarunporn; Teparrukkul, Prapit; Hantrakun, Viriya; Limmathurotsakul, Direk; Chantratita, Narisara; West, T Eoin.

Afiliação

Wright SW; Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Washington, Seattle, Washington, United States of America.
Lovelace-Macon L; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington, Seattle, Washington, United States of America.
Ducken D; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington, Seattle, Washington, United States of America.
Tandhavanant S; Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Teparrukkul P; Department of Internal Medicine, Sunpasitthiprasong Hospital, Ubon Ratchathani, Thailand.
Hantrakun V; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Limmathurotsakul D; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Chantratita N; Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
West TE; Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

PLoS Negl Trop Dis ; 14(8): e0008495, 2020 08.

Article em En | MEDLINE | ID: mdl-32764765

Assuntos

Infecções por Burkholderia/metabolismo; Infecções por Burkholderia/microbiologia; Burkholderia; Lactoferrina/metabolismo; Receptor 4 Toll-Like/metabolismo; Fator de Necrose Tumoral alfa/metabolismo; Burkholderia pseudomallei; Células Cultivadas; Humanos; Melioidose/metabolismo; Monócitos; Receptor 4 Toll-Like/genética; Fator de Necrose Tumoral alfa/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Necrose Tumoral alfa / Infecções por Burkholderia / Burkholderia / Receptor 4 Toll-Like / Lactoferrina Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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