The lncRNA ANRIL regulates endothelial dysfunction by targeting the let-7b/TGF-ßR1 signalling pathway.

Liu, Xianglan; Li, Shufeng; Yang, Yi; Sun, Yong; Yang, Qingyuan; Gu, Nan; Li, Jing; Huang, Tuo; Liu, Ying; Dong, Hui; Sun, Song; Fu, Guosheng; Wu, Jian; Yu, Bo

Liu, Xianglan; Li, Shufeng; Yang, Yi; Sun, Yong; Yang, Qingyuan; Gu, Nan; Li, Jing; Huang, Tuo; Liu, Ying; Dong, Hui; Sun, Song; Fu, Guosheng; Wu, Jian; Yu, Bo.

Afiliação

Liu X; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Li S; The Key Laboratory of Myocardial Ischaemia, Harbin Medical University, Ministry of Education, Harbin, Heilongjiang, China.
Yang Y; Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Sun Y; The Key Laboratory of Myocardial Ischaemia, Harbin Medical University, Ministry of Education, Harbin, Heilongjiang, China.
Yang Q; Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Gu N; The Key Laboratory of Myocardial Ischaemia, Harbin Medical University, Ministry of Education, Harbin, Heilongjiang, China.
Li J; Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Huang T; The Key Laboratory of Myocardial Ischaemia, Harbin Medical University, Ministry of Education, Harbin, Heilongjiang, China.
Liu Y; Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Dong H; The Key Laboratory of Myocardial Ischaemia, Harbin Medical University, Ministry of Education, Harbin, Heilongjiang, China.
Sun S; Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Fu G; The Key Laboratory of Myocardial Ischaemia, Harbin Medical University, Ministry of Education, Harbin, Heilongjiang, China.
Wu J; Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Yu B; The Key Laboratory of Myocardial Ischaemia, Harbin Medical University, Ministry of Education, Harbin, Heilongjiang, China.

J Cell Physiol ; 236(3): 2058-2069, 2021 03.

Article em En | MEDLINE | ID: mdl-32783191

Assuntos

Células Endoteliais da Veia Umbilical Humana/metabolismo; Células Endoteliais da Veia Umbilical Humana/patologia; MicroRNAs/metabolismo; RNA Longo não Codificante/metabolismo; Receptor do Fator de Crescimento Transformador beta Tipo I/metabolismo; Transdução de Sinais; Síndrome Coronariana Aguda/genética; Sequência de Bases; Biomarcadores/metabolismo; Humanos; Inflamação/genética; Inflamação/patologia; Modelos Biológicos; RNA Longo não Codificante/genética; RNA Mensageiro/genética; RNA Mensageiro/metabolismo; Transdução de Sinais/genética; Proteínas Smad/metabolismo; Regulação para Cima/genética

Palavras-chave

ANRIL; coronary artery disease; endothelial dysfunction; inflammatory; let-7b

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / MicroRNAs / Células Endoteliais da Veia Umbilical Humana / RNA Longo não Codificante / Receptor do Fator de Crescimento Transformador beta Tipo I Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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