Spinal interleukin-6 contributes to central sensitisation and persistent pain hypersensitivity in a model of juvenile idiopathic arthritis.

Kwok, Charlie H T; Learoyd, Annastazia E; Canet-Pons, Julia; Trang, Tuan; Fitzgerald, Maria

Kwok, Charlie H T; Learoyd, Annastazia E; Canet-Pons, Julia; Trang, Tuan; Fitzgerald, Maria.

Afiliação

Kwok CHT; Physiology and Pharmacology, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada; Comparative Biology and Experimental Medicine, University of Calgary, Calgary, Alberta, Canada. Electronic address: hongting.kwok@ucalgary.ca.
Learoyd AE; Department of Neuroscience, Physiology and Pharmacology, University College London, UK.
Canet-Pons J; Physiology and Pharmacology, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada; Comparative Biology and Experimental Medicine, University of Calgary, Calgary, Alberta, Canada.
Trang T; Physiology and Pharmacology, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada; Comparative Biology and Experimental Medicine, University of Calgary, Calgary, Alberta, Canada.
Fitzgerald M; Department of Neuroscience, Physiology and Pharmacology, University College London, UK.

Brain Behav Immun ; 90: 145-154, 2020 11.

Article em En | MEDLINE | ID: mdl-32791212

Assuntos

Artrite Juvenil; Interleucina-6; Animais; Sensibilização do Sistema Nervoso Central; Hiperalgesia; Inflamação; Masculino; Dor; Ratos; Ratos Sprague-Dawley; Medula Espinal

Palavras-chave

Chronic pain; Electrophysiology; Inflammation; Interleukin-6; Juvenile arthritis; Sensory behaviour

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Juvenil / Interleucina-6 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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