Spatial coordinate corrected motion tracking for optical coherence elastography.
Proc SPIE Int Soc Opt Eng
; 112422020 Feb.
Article
em En
| MEDLINE
| ID: mdl-32801425
ABSTRACT
We develop a spatial coordinate corrected (SCC) motion tracking method for optical coherence elastography. SCC motion tracking refers the instantaneous velocity field extracted from optical coherence tomography (OCT) data to the laboratory coordinate system and accurately reconstructs the displacement field established during the mechanical excitation (compression) process. We acquired image data from compression OCE experiments on human breast tissue specimens, and reconstructed the displacement field through Doppler analysis of OCT data. Our results suggested that SCC tracking enables accurate reconstruction of displacement field, and enables effective identification mechanical heterogeneity that can be used as a biomarker for cancer diagnosis and tumor margin assessment.
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Coleções:
01-internacional
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MEDLINE
Idioma:
En
Ano de publicação:
2020
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Article