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Microparticles globally reprogram Streptomyces albus toward accelerated morphogenesis, streamlined carbon core metabolism, and enhanced production of the antituberculosis polyketide pamamycin.
Kuhl, Martin; Gläser, Lars; Rebets, Yuriy; Rückert, Christian; Sarkar, Namrata; Hartsch, Thomas; Kalinowski, Jörn; Luzhetskyy, Andriy; Wittmann, Christoph.
Afiliação
  • Kuhl M; Institute of Systems Biotechnology, Saarland University, Saarbrücken, Germany.
  • Gläser L; Institute of Systems Biotechnology, Saarland University, Saarbrücken, Germany.
  • Rebets Y; Department of Pharmacy, Pharmaceutical Biotechnology, Saarland University, Saarbrücken, Germany.
  • Rückert C; Center for Biotechnology, Bielefeld University, Bielefeld, Germany.
  • Sarkar N; Genedata GmbH, Munich, Germany.
  • Hartsch T; Genedata GmbH, Munich, Germany.
  • Kalinowski J; Center for Biotechnology, Bielefeld University, Bielefeld, Germany.
  • Luzhetskyy A; Department of Pharmacy, Pharmaceutical Biotechnology, Saarland University, Saarbrücken, Germany.
  • Wittmann C; Institute of Systems Biotechnology, Saarland University, Saarbrücken, Germany.
Biotechnol Bioeng ; 117(12): 3858-3875, 2020 12.
Article em En | MEDLINE | ID: mdl-32808679

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Streptomyces / Macrolídeos / Engenharia Metabólica Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Streptomyces / Macrolídeos / Engenharia Metabólica Idioma: En Ano de publicação: 2020 Tipo de documento: Article