Your browser doesn't support javascript.
loading
Endeavors towards transformation of M. tuberculosis thymidylate kinase (MtbTMPK) inhibitors into potential antimycobacterial agents.
Jian, Yanlin; Merceron, Romain; De Munck, Steven; Forbes, He Eun; Hulpia, Fabian; Risseeuw, Martijn D P; Van Hecke, Kristof; Savvides, Savvas N; Munier-Lehmann, Hélène; Boshoff, Helena I M; Van Calenbergh, Serge.
Afiliação
  • Jian Y; Laboratory for Medicinal Chemistry (FFW), Ghent University, Ottergemsesteenweg 460, B-9000, Ghent, Belgium.
  • Merceron R; VIB Center for Inflammation Research, Zwijnaarde, Ghent, 9052, Belgium; Department of Biochemistry and Microbiology, Ghent University, Ghent, 9052, Belgium.
  • De Munck S; VIB Center for Inflammation Research, Zwijnaarde, Ghent, 9052, Belgium; Department of Biochemistry and Microbiology, Ghent University, Ghent, 9052, Belgium.
  • Forbes HE; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD, 20892, United States.
  • Hulpia F; Laboratory for Medicinal Chemistry (FFW), Ghent University, Ottergemsesteenweg 460, B-9000, Ghent, Belgium.
  • Risseeuw MDP; Laboratory for Medicinal Chemistry (FFW), Ghent University, Ottergemsesteenweg 460, B-9000, Ghent, Belgium.
  • Van Hecke K; XStruct, Department of Chemistry, Ghent University, Krijgslaan 281 S3, Gent, B-9000, Belgium.
  • Savvides SN; VIB Center for Inflammation Research, Zwijnaarde, Ghent, 9052, Belgium; Department of Biochemistry and Microbiology, Ghent University, Ghent, 9052, Belgium.
  • Munier-Lehmann H; Unit of Chemistry and Biocatalysis, Department of Structural Biology and Chemistry, Institut Pasteur, CNRS UMR3523, 28 Rue du Dr. Roux, Cedex, 15 75724, Paris, France.
  • Boshoff HIM; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD, 20892, United States.
  • Van Calenbergh S; Laboratory for Medicinal Chemistry (FFW), Ghent University, Ottergemsesteenweg 460, B-9000, Ghent, Belgium. Electronic address: serge.vancalenbergh@ugent.be.
Eur J Med Chem ; 206: 112659, 2020 Nov 15.
Article em En | MEDLINE | ID: mdl-32823003
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Núcleosídeo-Fosfato Quinase / Inibidores Enzimáticos / Mycobacterium tuberculosis Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Núcleosídeo-Fosfato Quinase / Inibidores Enzimáticos / Mycobacterium tuberculosis Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article