SCF-FBXO24 regulates cell proliferation by mediating ubiquitination and degradation of PRMT6.

Chen, Wei; Gao, Denghui; Xie, Long; Wang, Anling; Zhao, Hui; Guo, Chaowan; Sun, Yunqi; Nie, Yanfeng; Hong, An; Xiong, Sheng

Chen, Wei; Gao, Denghui; Xie, Long; Wang, Anling; Zhao, Hui; Guo, Chaowan; Sun, Yunqi; Nie, Yanfeng; Hong, An; Xiong, Sheng.

Afiliação

Chen W; College of Life Science and Technology, Jinan University, Guangzhou, 510630, China.
Gao D; College of Life Science and Technology, Jinan University, Guangzhou, 510630, China; Department of Pharmacy, Yangtze University Affiliated Hospital Jingzhou, Hangkong Street 8, Jingzhou, 434000, China.
Xie L; Clinical & Translational Research Institute, Newcastle University, Newcastle, UK.
Wang A; College of Life Science and Technology, Jinan University, Guangzhou, 510630, China.
Zhao H; College of Life Science and Technology, Jinan University, Guangzhou, 510630, China.
Guo C; Guangdong Marubi Biotechnology Co., Ltd, Guangzhou, 510530, China.
Sun Y; Guangdong Marubi Biotechnology Co., Ltd, Guangzhou, 510530, China.
Nie Y; Guangdong Marubi Biotechnology Co., Ltd, Guangzhou, 510530, China.
Hong A; College of Life Science and Technology, Jinan University, Guangzhou, 510630, China; Institute of Biomedicine & National Engineering Research Center of Genetic Medicine, Guangzhou, 510630, China. Electronic address: tha@jnu.edu.cn.
Xiong S; College of Life Science and Technology, Jinan University, Guangzhou, 510630, China; Institute of Biomedicine & National Engineering Research Center of Genetic Medicine, Guangzhou, 510630, China. Electronic address: xsh_jnu@hotmail.com.

Biochem Biophys Res Commun ; 530(1): 75-81, 2020 09 10.

Article em En | MEDLINE | ID: mdl-32828318

Assuntos

Proteínas F-Box/metabolismo; Proteínas Nucleares/metabolismo; Proteína-Arginina N-Metiltransferases/metabolismo; Proteólise; Ubiquitinação; Sistemas CRISPR-Cas; Linhagem Celular Tumoral; Movimento Celular; Proliferação de Células; Proteínas F-Box/genética; Humanos; Mutação; Invasividade Neoplásica/genética; Neoplasias/genética; Neoplasias/metabolismo; Proteínas Nucleares/genética; Proteína-Arginina N-Metiltransferases/genética; Regulação para Cima

Palavras-chave

Cell cycle; Cell proliferation; FBXO24; Protein arginine methyltransferase 6; Ubiquitin-proteasome pathway

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína-Arginina N-Metiltransferases / Proteínas Nucleares / Proteínas F-Box / Ubiquitinação / Proteólise Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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