Sex-biased transgenerational transmission of betaine-induced epigenetic modifications in glucocorticoid receptor gene and its down-stream BDNF/ERK pathway in rat hippocampus.

Yang, Yang; Yang, Shu; Jia, Yimin; Yin, Chao; Zhao, Ruqian

Yang, Yang; Yang, Shu; Jia, Yimin; Yin, Chao; Zhao, Ruqian.

Afiliação

Yang Y; MOE Joint International Research Laboratory of Animal Health & Food Safety, Nanjing Agricultural University, Nanjing, People's Republic of China.
Yang S; Key Laboratory of Animal Physiology & Biochemistry, Nanjing Agricultural University, Nanjing, People's Republic of China.
Jia Y; MOE Joint International Research Laboratory of Animal Health & Food Safety, Nanjing Agricultural University, Nanjing, People's Republic of China.
Yin C; Key Laboratory of Animal Physiology & Biochemistry, Nanjing Agricultural University, Nanjing, People's Republic of China.
Zhao R; MOE Joint International Research Laboratory of Animal Health & Food Safety, Nanjing Agricultural University, Nanjing, People's Republic of China.

Nutr Neurosci ; 25(4): 746-757, 2022 Apr.

Article em En | MEDLINE | ID: mdl-32840180

Assuntos

Betaína; Receptores de Glucocorticoides; Animais; Betaína/metabolismo; Betaína/farmacologia; Fator Neurotrófico Derivado do Encéfalo/genética; Fator Neurotrófico Derivado do Encéfalo/metabolismo; Metilação de DNA; Epigênese Genética; Feminino; Glucocorticoides; Hipocampo/metabolismo; Sistema de Sinalização das MAP Quinases; Masculino; Ratos; Ratos Sprague-Dawley; Receptores de Glucocorticoides/genética; Receptores de Glucocorticoides/metabolismo

Palavras-chave

BDNF/ERK; Glucocorticoid receptor; betaine; hippocampus; sex-biased

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Betaína / Receptores de Glucocorticoides Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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