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Persistent IL-2 Receptor Signaling by IL-2/CD25 Fusion Protein Controls Diabetes in NOD Mice by Multiple Mechanisms.
Ward, Natasha C; Lui, Jen Bon; Hernandez, Rosmely; Yu, Liping; Struthers, Mary; Xie, Jenny; Santos Savio, Alicia; Dwyer, Connor J; Hsiung, Sunnie; Yu, Aixin; Malek, Thomas R.
Afiliação
  • Ward NC; Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL.
  • Lui JB; Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL.
  • Hernandez R; Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL.
  • Yu L; Barbara Davis Center for Childhood Diabetes, University of Colorado School of Medicine, Aurora, CO.
  • Struthers M; Immunology Discovery, Bristol-Myers Squibb, Princeton, NJ.
  • Xie J; Immunology Discovery, Bristol-Myers Squibb, Princeton, NJ.
  • Santos Savio A; Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL.
  • Dwyer CJ; Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL.
  • Hsiung S; Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL.
  • Yu A; Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL.
  • Malek TR; Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL tmalek@med.miami.edu.
Diabetes ; 69(11): 2400-2413, 2020 11.
Article em En | MEDLINE | ID: mdl-32843568
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Interleucina-2 / Transdução de Sinais / Interleucina-2 / Diabetes Mellitus / Subunidade alfa de Receptor de Interleucina-2 Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Interleucina-2 / Transdução de Sinais / Interleucina-2 / Diabetes Mellitus / Subunidade alfa de Receptor de Interleucina-2 Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article