miR-130b-3p regulates M1 macrophage polarization via targeting IRF1.

Guo, Qiang; Zhu, Xiaoxiao; Wei, Ran; Zhao, Lin; Zhang, Zhen; Yin, Xunqiang; Zhang, Yunhong; Chu, Chu; Wang, Bin; Li, Xia

Guo, Qiang; Zhu, Xiaoxiao; Wei, Ran; Zhao, Lin; Zhang, Zhen; Yin, Xunqiang; Zhang, Yunhong; Chu, Chu; Wang, Bin; Li, Xia.

Afiliação

Guo Q; Laboratory for Molecular Immunology, Institute of Basic Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Zhu X; Laboratory for Molecular Immunology, Institute of Basic Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Wei R; Laboratory for Molecular Immunology, Institute of Basic Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Zhao L; Laboratory for Molecular Immunology, Institute of Basic Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Zhang Z; Laboratory for Molecular Immunology, Institute of Basic Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Yin X; Laboratory for Molecular Immunology, Institute of Basic Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Zhang Y; School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Chu C; Laboratory for Molecular Immunology, Institute of Basic Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Wang B; School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Li X; Laboratory for Molecular Immunology, Institute of Basic Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.

J Cell Physiol ; 236(3): 2008-2022, 2021 03.

Article em En | MEDLINE | ID: mdl-32853398

Assuntos

Polaridade Celular/genética; Fator Regulador 1 de Interferon/metabolismo; Macrófagos/citologia; Macrófagos/metabolismo; MicroRNAs/metabolismo; Regiões 3' não Traduzidas/genética; Animais; Sequência de Bases; Polaridade Celular/efeitos dos fármacos; Quimiocina CCL5/metabolismo; Quimiocina CXCL10/metabolismo; Regulação para Baixo/efeitos dos fármacos; Inflamação/genética; Inflamação/patologia; Fator Regulador 1 de Interferon/genética; Interferon gama/farmacologia; Lipopolissacarídeos/farmacologia; Pulmão/patologia; Macrófagos/efeitos dos fármacos; Masculino; Camundongos; Camundongos Endogâmicos C57BL; MicroRNAs/genética; Óxido Nítrico Sintase Tipo II/metabolismo; Células RAW 264.7; RNA Mensageiro/genética; RNA Mensageiro/metabolismo; Fator de Necrose Tumoral alfa/metabolismo; Regulação para Cima/efeitos dos fármacos; Regulação para Cima/genética

Palavras-chave

IRF1; M1 macrophage; macrophage polarization; miR-130b-3p; noncoding RNA

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polaridade Celular / MicroRNAs / Fator Regulador 1 de Interferon / Macrófagos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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