In vitro, ex vivo and in vivo evaluation of taste masked low dose acetylsalicylic acid loaded composite wafers as platforms for buccal administration in geriatric patients with dysphagia.

Farias, Smirna; Boateng, Joshua S

Farias, Smirna; Boateng, Joshua S.

Afiliação

Farias S; School of Science, Faculty of Engineering and Science, University of Greenwich at Medway, Chatham Maritime, Kent ME4 4TB, UK.
Boateng JS; School of Science, Faculty of Engineering and Science, University of Greenwich at Medway, Chatham Maritime, Kent ME4 4TB, UK. Electronic address: j.s.boateng@gre.ac.uk.

Int J Pharm ; 589: 119807, 2020 Nov 15.

Article em En | MEDLINE | ID: mdl-32882368

Assuntos

Aspirina; Transtornos de Deglutição; Administração Bucal; Idoso; Animais; Chlorocebus aethiops; Sistemas de Liberação de Medicamentos; Humanos; Suínos; Paladar; Células Vero

Palavras-chave

Acetylsalicylic acid; Aspartame; Buccal mucosa; Drug permeation; Geriatric patients; Sucralose; Taste masking

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtornos de Deglutição / Aspirina Limite: Aged / Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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