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From orexin receptor agonist YNT-185 to novel antagonists with drug-like properties for the treatment of insomnia.
Mezeiova, Eva; Janockova, Jana; Konecny, Jan; Kobrlova, Tereza; Benkova, Marketa; Dolezal, Rafael; Prchal, Lukas; Karasova-Zdarova, Jana; Soukup, Ondrej; Korabecny, Jan.
Afiliação
  • Mezeiova E; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic.
  • Janockova J; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic.
  • Konecny J; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic.
  • Kobrlova T; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic.
  • Benkova M; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic.
  • Dolezal R; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic.
  • Prchal L; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic.
  • Karasova-Zdarova J; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic.
  • Soukup O; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic. Electronic address: ondrej.soukup@fnhk.cz.
  • Korabecny J; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic. Electronic address: jan.korabecny@fnhk.cz.
Bioorg Chem ; 103: 104179, 2020 10.
Article em En | MEDLINE | ID: mdl-32891860
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzamidas / Receptores de Orexina / Distúrbios do Início e da Manutenção do Sono / Compostos de Anilina Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzamidas / Receptores de Orexina / Distúrbios do Início e da Manutenção do Sono / Compostos de Anilina Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article