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Polygenic architecture informs potential vulnerability to drug-induced liver injury.
Koido, Masaru; Kawakami, Eri; Fukumura, Junko; Noguchi, Yui; Ohori, Momoko; Nio, Yasunori; Nicoletti, Paola; Aithal, Guruprasad P; Daly, Ann K; Watkins, Paul B; Anayama, Hisashi; Dragan, Yvonne; Shinozawa, Tadahiro; Takebe, Takanori.
Afiliação
  • Koido M; Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan.
  • Kawakami E; Organoid Medicine Project, T-CiRA Joint Program, Fujisawa, Kanagawa, Japan.
  • Fukumura J; Organoid Medicine Project, T-CiRA Joint Program, Fujisawa, Kanagawa, Japan.
  • Noguchi Y; T-CiRA Discovery, Takeda Pharmaceutical Company, Fujisawa, Kanagawa, Japan.
  • Ohori M; Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan.
  • Nio Y; Organoid Medicine Project, T-CiRA Joint Program, Fujisawa, Kanagawa, Japan.
  • Nicoletti P; Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan.
  • Aithal GP; Organoid Medicine Project, T-CiRA Joint Program, Fujisawa, Kanagawa, Japan.
  • Daly AK; Organoid Medicine Project, T-CiRA Joint Program, Fujisawa, Kanagawa, Japan.
  • Watkins PB; T-CiRA Discovery, Takeda Pharmaceutical Company, Fujisawa, Kanagawa, Japan.
  • Anayama H; Organoid Medicine Project, T-CiRA Joint Program, Fujisawa, Kanagawa, Japan.
  • Dragan Y; T-CiRA Discovery, Takeda Pharmaceutical Company, Fujisawa, Kanagawa, Japan.
  • Shinozawa T; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Takebe T; NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, UK.
Nat Med ; 26(10): 1541-1548, 2020 10.
Article em En | MEDLINE | ID: mdl-32895570
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Herança Multifatorial / Polimorfismo de Nucleotídeo Único / Doença Hepática Induzida por Substâncias e Drogas Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Herança Multifatorial / Polimorfismo de Nucleotídeo Único / Doença Hepática Induzida por Substâncias e Drogas Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article