Activity and specificity studies of the new thermostable esterase EstDZ2.
Bioorg Chem
; 104: 104214, 2020 11.
Article
em En
| MEDLINE
| ID: mdl-32927128
ABSTRACT
In this paper, we study the activity and specificity of EstDZ2, a new thermostable carboxyl esterase of unknown function, which was isolated from a metagenome library from a Russian hot spring. The biocatalytic reaction employing EstDZ2 proved to be an efficient method for the hydrolysis of aryl p-, o- or m-substituted esters of butyric acid and esters of secondary alcohols. Docking studies revealed structural features of the enzyme that led to activity differences among the different substrates.
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1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Temperatura
/
Esterases
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article