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Synthetic lethal combination targeting BET uncovered intrinsic susceptibility of TNBC to ferroptosis.
Verma, Nandini; Vinik, Yaron; Saroha, Ashish; Nair, Nishanth Ulhas; Ruppin, Eytan; Mills, Gordon; Karn, Thomas; Dubey, Vinay; Khera, Lohit; Raj, Harsha; Maina, Flavio; Lev, Sima.
Afiliação
  • Verma N; Molecular Cell Biology Department, Weizmann Institute of Science, Rehovot 20892, Israel.
  • Vinik Y; Molecular Cell Biology Department, Weizmann Institute of Science, Rehovot 20892, Israel.
  • Saroha A; Molecular Cell Biology Department, Weizmann Institute of Science, Rehovot 20892, Israel.
  • Nair NU; Cancer Data Science Laboratory, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  • Ruppin E; Cancer Data Science Laboratory, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  • Mills G; Knight Cancer Institute, Portland, OR 97201, USA.
  • Karn T; Department of Obstetrics and Gynecology, Goethe University, D-60323 Frankfurt, Germany.
  • Dubey V; Molecular Cell Biology Department, Weizmann Institute of Science, Rehovot 20892, Israel.
  • Khera L; Molecular Cell Biology Department, Weizmann Institute of Science, Rehovot 20892, Israel.
  • Raj H; Molecular Cell Biology Department, Weizmann Institute of Science, Rehovot 20892, Israel.
  • Maina F; Aix Marseille Univ, CNRS, Developmental Biology Institute of Marseille (IBDM) UMR 7288, Marseille, France.
  • Lev S; Molecular Cell Biology Department, Weizmann Institute of Science, Rehovot 20892, Israel. sima.lev@weizmann.ac.il.
Sci Adv ; 6(34)2020 08.
Article em En | MEDLINE | ID: mdl-32937365
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article