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Trem2 promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions.
Liu, Wenfei; Taso, Orjona; Wang, Rui; Bayram, Sevinc; Graham, Andrew C; Garcia-Reitboeck, Pablo; Mallach, Anna; Andrews, William D; Piers, Thomas M; Botia, Juan A; Pocock, Jennifer M; Cummings, Damian M; Hardy, John; Edwards, Frances A; Salih, Dervis A.
Afiliação
  • Liu W; Department of Neuroscience, Physiology and Pharmacology, UCL, London WC1E 6BT, UK.
  • Taso O; UK Dementia Research Institute at UCL, London WC1E 6BT, UK.
  • Wang R; Department of Neuroscience, Physiology and Pharmacology, UCL, London WC1E 6BT, UK.
  • Bayram S; Hitachi Rail Europe Ltd, London EC1N 2PB, UK.
  • Graham AC; UK Dementia Research Institute at UCL, London WC1E 6BT, UK.
  • Garcia-Reitboeck P; Department of Neuroinflammation, Institute of Neurology, UCL, London WC1N 1PJ, UK.
  • Mallach A; Department of Neuroinflammation, Institute of Neurology, UCL, London WC1N 1PJ, UK.
  • Andrews WD; Department of Cell and Developmental Biology, UCL, London WC1E 6BT, UK.
  • Piers TM; Department of Neuroinflammation, Institute of Neurology, UCL, London WC1N 1PJ, UK.
  • Botia JA; Department of Information and Communications Engineering, Universidad de Murcia, Murcia E-30100, Spain.
  • Pocock JM; Department of Neurodegenerative Diseases, Institute of Neurology, UCL, London WC1N 1PJ, UK.
  • Cummings DM; Department of Neuroinflammation, Institute of Neurology, UCL, London WC1N 1PJ, UK.
  • Hardy J; Department of Neuroscience, Physiology and Pharmacology, UCL, London WC1E 6BT, UK.
  • Edwards FA; UK Dementia Research Institute at UCL, London WC1E 6BT, UK.
  • Salih DA; Department of Neurodegenerative Diseases, Institute of Neurology, UCL, London WC1N 1PJ, UK.
Hum Mol Genet ; 29(19): 3224-3248, 2020 11 25.
Article em En | MEDLINE | ID: mdl-32959884
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Receptores Imunológicos / Regulação da Expressão Gênica / Microglia / Mediadores da Inflamação / Transcriptoma / Inflamação / Mutação Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Receptores Imunológicos / Regulação da Expressão Gênica / Microglia / Mediadores da Inflamação / Transcriptoma / Inflamação / Mutação Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article