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Translation elongation factor 2 depletion by siRNA in mouse liver leads to mTOR-independent translational upregulation of ribosomal protein genes.
Gerashchenko, Maxim V; Nesterchuk, Mikhail V; Smekalova, Elena M; Paulo, Joao A; Kowalski, Piotr S; Akulich, Kseniya A; Bogorad, Roman; Dmitriev, Sergey E; Gygi, Steven; Zatsepin, Timofei; Anderson, Daniel G; Gladyshev, Vadim N; Koteliansky, Victor E.
Afiliação
  • Gerashchenko MV; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA. mgerashchenko@bwh.harvard.edu.
  • Nesterchuk MV; Skolkovo Institute of Science and Technology, Skolkovo, Moscow Region, Russia.
  • Smekalova EM; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA.
  • Paulo JA; Department of Cell Biology, Harvard Medical School, Boston, MA, 02115, USA.
  • Kowalski PS; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA.
  • Akulich KA; Belozersky Institute of Physico-Chemical Biology, Moscow State University, Moscow, 119992, Russia.
  • Bogorad R; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA.
  • Dmitriev SE; Belozersky Institute of Physico-Chemical Biology, Moscow State University, Moscow, 119992, Russia.
  • Gygi S; Department of Cell Biology, Harvard Medical School, Boston, MA, 02115, USA.
  • Zatsepin T; Skolkovo Institute of Science and Technology, Skolkovo, Moscow Region, Russia.
  • Anderson DG; Department of Chemistry, Lomonosov Moscow State University, Moscow, Russia.
  • Gladyshev VN; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA.
  • Koteliansky VE; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Sci Rep ; 10(1): 15473, 2020 09 23.
Article em En | MEDLINE | ID: mdl-32968084
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Ribossômicas / RNA Interferente Pequeno / Quinase do Fator 2 de Elongação / Serina-Treonina Quinases TOR / Fígado Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Ribossômicas / RNA Interferente Pequeno / Quinase do Fator 2 de Elongação / Serina-Treonina Quinases TOR / Fígado Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article