Engineered U7 Small Nuclear RNA Restores Correct ß-Globin Pre-mRNA Splicing in Mouse ß<sup>IVS2-654</sup>-Thalassemic Erythroid Progenitor Cells.

d'Arqom, Annette; Nualkaew, Tiwaporn; Jearawiriyapaisarn, Natee; Kole, Ryszard; Svasti, Saovaros

Engineered U7 Small Nuclear RNA Restores Correct ß-Globin Pre-mRNA Splicing in Mouse ß^IVS2-654-Thalassemic Erythroid Progenitor Cells.

d'Arqom, Annette; Nualkaew, Tiwaporn; Jearawiriyapaisarn, Natee; Kole, Ryszard; Svasti, Saovaros.

Afiliação

d'Arqom A; Graduate Program in Molecular Medicine.
Nualkaew T; Thalassemia Research Center, Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom, Thailand.
Jearawiriyapaisarn N; Department of Pharmacology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
Kole R; Thalassemia Research Center, Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom, Thailand.
Svasti S; Thalassemia Research Center, Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom, Thailand.

Hum Gene Ther ; 32(9-10): 473-480, 2021 05.

Article em En | MEDLINE | ID: mdl-32977730

Assuntos

Precursores de RNA; Globinas beta; Animais; Células Precursoras Eritroides/metabolismo; Humanos; Camundongos; Precursores de RNA/genética; Precursores de RNA/metabolismo; Splicing de RNA/genética; RNA Nuclear Pequeno/genética; RNA Nuclear Pequeno/metabolismo; Globinas beta/genética

Palavras-chave

RNA splicing; U7 snRNA; thalassemia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Precursores de RNA / Globinas beta Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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