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Blockade of Kv1.3 potassium channel inhibits CD8+ T cell-mediated neuroinflammation via PD-1/Blimp-1 signaling.
Zhao, Yipeng; Qiu, Wei; Liu, Junchen; Yuan, Xiaolu; Mao, Wenqian; Yin, Jun; Peng, BiWen; Liu, WanHong; Han, Song; He, XiaoHua.
Afiliação
  • Zhao Y; Department of Pathophysiology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
  • Qiu W; Department of Neurology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
  • Liu J; Department of Neurology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
  • Yuan X; Department of Pathophysiology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
  • Mao W; Department of Pathophysiology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
  • Yin J; Department of Pathophysiology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
  • Peng B; Department of Pathophysiology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
  • Liu W; Hubei Provincial Key Laboratory of Developmentally Originated Disease, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
  • Han S; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
  • He X; Department of Pathophysiology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
FASEB J ; 34(11): 15492-15503, 2020 11.
Article em En | MEDLINE | ID: mdl-32981181
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T CD8-Positivos / Bloqueadores dos Canais de Potássio / Encefalomielite Autoimune Experimental / Canal de Potássio Kv1.3 / Receptor de Morte Celular Programada 1 / Fator 1 de Ligação ao Domínio I Regulador Positivo / Inflamação Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T CD8-Positivos / Bloqueadores dos Canais de Potássio / Encefalomielite Autoimune Experimental / Canal de Potássio Kv1.3 / Receptor de Morte Celular Programada 1 / Fator 1 de Ligação ao Domínio I Regulador Positivo / Inflamação Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article