Impact of Obesity on Voriconazole Pharmacokinetics among Pediatric Hematopoietic Cell Transplant Recipients.

Takahashi, Takuto; Smith, Angela R; Jacobson, Pamala A; Fisher, James; Rubin, Nathan T; Kirstein, Mark N

Takahashi, Takuto; Smith, Angela R; Jacobson, Pamala A; Fisher, James; Rubin, Nathan T; Kirstein, Mark N.

Afiliação

Takahashi T; Division of Hematology and Oncology, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
Smith AR; Division of Blood and Marrow Transplant, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
Jacobson PA; Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, Minnesota, USA.
Fisher J; Division of Blood and Marrow Transplant, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
Rubin NT; Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, Minnesota, USA.
Kirstein MN; Clinical Pharmacology Analytical Services, University of Minnesota, Minneapolis, Minnesota, USA.

Antimicrob Agents Chemother ; 64(12)2020 11 17.

Article em En | MEDLINE | ID: mdl-32988816

Assuntos

Antifúngicos; Transplante de Células-Tronco Hematopoéticas; Obesidade; Transplantados; Voriconazol; Adolescente; Antifúngicos/uso terapêutico; Criança; Pré-Escolar; Citocromo P-450 CYP2C19/genética; Humanos; Masculino; Obesidade/complicações; Voriconazol/farmacocinética; Adulto Jovem

Palavras-chave

CYP2C19; obesity; pharmacogenomics; voriconazole; voriconazole N-oxide

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante de Células-Tronco Hematopoéticas / Voriconazol / Transplantados / Antifúngicos / Obesidade Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Child / Child, preschool / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google