Metabolic dysfunction in human skin: Restoration of mitochondrial integrity and metabolic output by nicotinamide (niacinamide) in primary dermal fibroblasts from older aged donors.

Oblong, John E; Bowman, Amy; Rovito, Holly A; Jarrold, Bradley B; Sherrill, Joseph D; Black, Markaisa R; Nelson, Glyn; Kimball, Alexa B; Birch-Machin, Mark A

Oblong, John E; Bowman, Amy; Rovito, Holly A; Jarrold, Bradley B; Sherrill, Joseph D; Black, Markaisa R; Nelson, Glyn; Kimball, Alexa B; Birch-Machin, Mark A.

Afiliação

Oblong JE; The Procter & Gamble Company, Cincinnati, OH, USA.
Bowman A; Dermatological Sciences, Translational and Clinical Research Institute, Medical School, Newcastle University, Newcastle upon Tyne, UK.
Rovito HA; The Procter & Gamble Company, Cincinnati, OH, USA.
Jarrold BB; The Procter & Gamble Company, Cincinnati, OH, USA.
Sherrill JD; The Procter & Gamble Company, Cincinnati, OH, USA.
Black MR; The Procter & Gamble Company, Cincinnati, OH, USA.
Nelson G; The Bioimaging Unit, William Leech Building, Newcastle University, Newcastle upon Tyne, UK.
Kimball AB; Harvard Medical School, Boston, MA, USA.
Birch-Machin MA; Dermatological Sciences, Translational and Clinical Research Institute, Medical School, Newcastle University, Newcastle upon Tyne, UK.

Aging Cell ; 19(10): e13248, 2020 10.

Article em En | MEDLINE | ID: mdl-32990346

Assuntos

Fibroblastos/metabolismo; Mitocôndrias/metabolismo; Niacinamida/metabolismo; Pele/patologia; Adulto; Idoso; Células Cultivadas; Humanos; Pessoa de Meia-Idade; Doadores de Tecidos; Adulto Jovem

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pele / Niacinamida / Fibroblastos / Mitocôndrias Limite: Adult / Aged / Humans / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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