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Furin Inhibitors Block SARS-CoV-2 Spike Protein Cleavage to Suppress Virus Production and Cytopathic Effects.
Cheng, Ya-Wen; Chao, Tai-Ling; Li, Chiao-Ling; Chiu, Mu-Fan; Kao, Han-Chieh; Wang, Sheng-Han; Pang, Yu-Hao; Lin, Chih-Hui; Tsai, Ya-Min; Lee, Wen-Hau; Tao, Mi-Hua; Ho, Tung-Ching; Wu, Ping-Yi; Jang, Li-Ting; Chen, Pei-Jer; Chang, Sui-Yuan; Yeh, Shiou-Hwei.
Afiliação
  • Cheng YW; Department of Microbiology, National Taiwan University College of Medicine, Taipei 100, Taiwan.
  • Chao TL; Department of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, Taipei 100, Taiwan.
  • Li CL; Department of Microbiology, National Taiwan University College of Medicine, Taipei 100, Taiwan.
  • Chiu MF; Department of Microbiology, National Taiwan University College of Medicine, Taipei 100, Taiwan.
  • Kao HC; Department of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, Taipei 100, Taiwan.
  • Wang SH; Hepatitis Research Center, National Taiwan University Hospital, Taipei 100, Taiwan.
  • Pang YH; Department of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, Taipei 100, Taiwan.
  • Lin CH; Department of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, Taipei 100, Taiwan.
  • Tsai YM; Department of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, Taipei 100, Taiwan.
  • Lee WH; Department of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, Taipei 100, Taiwan.
  • Tao MH; Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan.
  • Ho TC; Department of Microbiology, National Taiwan University College of Medicine, Taipei 100, Taiwan.
  • Wu PY; Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan.
  • Jang LT; Biomedical Resource Core at the First Core Labs, Branch Office of Research and Development, National Taiwan University College of Medicine, Taipei 100, Taiwan.
  • Chen PJ; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei 100, Taiwan; Department of Internal Medicine, National Taiwan University Hospital, Taipei 100, Taiwan; National Taiwan University Center for Genomic Medicine, National Taiwan University College of Medicin
  • Chang SY; Department of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, Taipei 100, Taiwan; Department of Laboratory Medicine, National Taiwan University Hospital, Taipei 100, Taiwan. Electronic address: sychang@ntu.edu.tw.
  • Yeh SH; Department of Microbiology, National Taiwan University College of Medicine, Taipei 100, Taiwan; Department of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, Taipei 100, Taiwan; National Taiwan University Center for Genomic Medicine, National T
Cell Rep ; 33(2): 108254, 2020 10 13.
Article em En | MEDLINE | ID: mdl-33007239
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Inibidores de Proteases / Replicação Viral / Furina / Glicoproteína da Espícula de Coronavírus / Fluoresceínas / Clorometilcetonas de Aminoácidos Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Inibidores de Proteases / Replicação Viral / Furina / Glicoproteína da Espícula de Coronavírus / Fluoresceínas / Clorometilcetonas de Aminoácidos Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article