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Pepper component 7-ethoxy-4-methylcoumarin, a novel dopamine D2 receptor agonist, ameliorates experimental Parkinson's disease in mice and Caenorhabditis elegans.
Li, Hongli; Feng, Yaru; Chen, Ziyu; Jiang, Xi; Zhou, Zhenyu; Yuan, Jinfeng; Li, Fei; Zhang, Yu; Huang, Xingxu; Fan, Shengjie; Wu, Xiaojun; Huang, Cheng.
Afiliação
  • Li H; Drug Discovery Laboratory, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
  • Feng Y; Drug Discovery Laboratory, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
  • Chen Z; Shanghai Key Laboratory of Compound Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
  • Jiang X; Drug Discovery Laboratory, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
  • Zhou Z; Drug Discovery Laboratory, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
  • Yuan J; Shanghai Key Laboratory of Compound Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
  • Li F; School of Life Science and Technology, Shanghai Tech University, Shanghai, China.
  • Zhang Y; School of Life Science and Technology, Shanghai Tech University, Shanghai, China.
  • Huang X; School of Life Science and Technology, Shanghai Tech University, Shanghai, China.
  • Fan S; Drug Discovery Laboratory, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China. Electronic address: fanshengjie@shutcm.edu.cn.
  • Wu X; Shanghai Key Laboratory of Compound Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, China. Electronic address: xiaojunwu320@126.com.
  • Huang C; Drug Discovery Laboratory, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China. Electronic address: chuang@shutcm.edu.cn.
Pharmacol Res ; 163: 105220, 2021 01.
Article em En | MEDLINE | ID: mdl-33007422
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fármacos Neuroprotetores / Agonistas de Dopamina / Cumarínicos / Transtornos Parkinsonianos Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fármacos Neuroprotetores / Agonistas de Dopamina / Cumarínicos / Transtornos Parkinsonianos Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article