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Piperlonguminine and Piperine Analogues as TrxR Inhibitors that Promote ROS and Autophagy and Regulate p38 and Akt/mTOR Signaling.
Zhu, Peng; Qian, Jianqiang; Xu, Zhongyuan; Meng, Chi; Liu, Ji; Shan, Wenpei; Zhu, Weizhong; Wang, Yongjun; Yang, Yumin; Zhang, Wei; Zhang, Yanan; Ling, Yong.
Afiliação
  • Zhu P; School of Pharmacy and Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong 226001, People's Republic of China.
  • Qian J; State Key Laboratory of Quality Research in Chinese Medicines, Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, Macau, People's Republic of China.
  • Xu Z; School of Pharmacy and Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong 226001, People's Republic of China.
  • Meng C; School of Pharmacy and Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong 226001, People's Republic of China.
  • Liu J; School of Pharmacy and Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong 226001, People's Republic of China.
  • Shan W; School of Pharmacy and Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong 226001, People's Republic of China.
  • Zhu W; School of Pharmacy and Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong 226001, People's Republic of China.
  • Wang Y; School of Pharmacy and Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong 226001, People's Republic of China.
  • Yang Y; Key Laboratory of Neuroregeneration, Ministry of Education and Jiangsu Province, Co-innovation Center of Neuroregeneration, Jiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury Repair, Nantong University, Nantong 226001, People's Republic of China.
  • Zhang W; School of Pharmacy and Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong 226001, People's Republic of China.
  • Zhang Y; Key Laboratory of Neuroregeneration, Ministry of Education and Jiangsu Province, Co-innovation Center of Neuroregeneration, Jiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury Repair, Nantong University, Nantong 226001, People's Republic of China.
  • Ling Y; State Key Laboratory of Quality Research in Chinese Medicines, Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, Macau, People's Republic of China.
J Nat Prod ; 83(10): 3041-3049, 2020 10 23.
Article em En | MEDLINE | ID: mdl-33026807
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperidinas / Autofagia / Transdução de Sinais / Proteínas Quinases p38 Ativadas por Mitógeno / Dioxolanos / Alcaloides / Benzodioxóis / Proteína Oncogênica v-akt / Alcamidas Poli-Insaturadas / Tiorredoxina Redutase 1 Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperidinas / Autofagia / Transdução de Sinais / Proteínas Quinases p38 Ativadas por Mitógeno / Dioxolanos / Alcaloides / Benzodioxóis / Proteína Oncogênica v-akt / Alcamidas Poli-Insaturadas / Tiorredoxina Redutase 1 Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article