A Designer Quest for the Achilles' Heel of Influenza.

Fajardo, J Eduardo; Fiser, Andras

Fajardo, J Eduardo; Fiser, Andras.

Afiliação

Fajardo JE; Department of Systems and Computational Biology, Albert Einstein College of Medicine, 1301 Morris Park Ave, Bronx, NY 10461, USA; Department of Biochemistry, Albert Einstein College of Medicine, 1301 Morris Park Ave, Bronx, NY 10461, USA.
Fiser A; Department of Systems and Computational Biology, Albert Einstein College of Medicine, 1301 Morris Park Ave, Bronx, NY 10461, USA; Department of Biochemistry, Albert Einstein College of Medicine, 1301 Morris Park Ave, Bronx, NY 10461, USA. Electronic address: andras.fiser@einsteinmed.org.

Structure ; 28(10): 1083-1084, 2020 10 06.

Article em En | MEDLINE | ID: mdl-33027689

ABSTRACT

ABSTRACT

Monoclonal antibodies are attractive but, in certain applications, limited therapeutic modalities due to their large size and high specificity. In this issue of Structure, Sevy at al. describe a computationally designed cyclic peptide mimicking the CDRH3 loop of the C05 antibody against influenza showing the potential utility of designer biologics.

Assuntos

Influenza Humana; Anticorpos Monoclonais; Fenômenos Biofísicos; Humanos; Influenza Humana/diagnóstico; Peptídeos Cíclicos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Influenza Humana Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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