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How Can Galectin-3 as a Biomarker of Fibrosis Improve Atrial Fibrillation Diagnosis and Prognosis?
da Silveira, Maria Mariana Barros Melo; Cabral, Joao Victor Batista; Souza, Bruno de Melo; Hazime, Louis Hussein Patu; Araujo, Sara Larissa de Melo; Xavier, Amanda Tavares; Mendes Filho, Edivaldo Bezerra; Vasconcelos, Luydson Richardson da Silva; Sobral Filho, Dario Celestino; de Oliveira, Dinaldo Cavalcanti.
Afiliação
  • da Silveira MMBM; Postgraduate Program in Therapeutic Innovation, Federal University of Pernambuco (PPGIT/UFPE), Recife, PE, Brazil.
  • Cabral JVB; Pernambuco Cardiovascular Emergency Room Teacher Luiz Tavares (PROCAPE/UPE), Recife, PE, Brazil.
  • Souza BM; Postgraduate Program in Therapeutic Innovation, Federal University of Pernambuco (PPGIT/UFPE), Recife, PE, Brazil.
  • Hazime LHP; Faculty of Medical Sciences, University of Pernambuco (FCM/UPE), Recife, PE, Brazil.
  • Araujo SLM; Faculty of Medical Sciences, University of Pernambuco (FCM/UPE), Recife, PE, Brazil.
  • Xavier AT; Health and Biological Sciences Program, University of Vale do Sao Francisco (PPGCSB/UNIVASF), Petrolina, PE, Brazil.
  • Mendes Filho EB; Faculty of Medical Sciences, University of Pernambuco (FCM/UPE), Recife, PE, Brazil.
  • Vasconcelos LRDS; Aggeu Magalhaes Institute, Oswaldo Cruz Foundation (Fiocruz), Recife, PE, Brazil.
  • Sobral Filho DC; Postgraduate Program in Therapeutic Innovation, Federal University of Pernambuco (PPGIT/UFPE), Recife, PE, Brazil.
  • de Oliveira DC; Aggeu Magalhaes Institute, Oswaldo Cruz Foundation (Fiocruz), Recife, PE, Brazil.
J Clin Med Res ; 12(10): 647-654, 2020 Oct.
Article em En | MEDLINE | ID: mdl-33029271
ABSTRACT
Galectin-3 (Gal-3) is a biomarker of fibrosis that has been associated with atrial remodeling. Acknowledging the presence of a biomarker in patients with atrial fibrillation (AF) can allow for a better clinical treatment. The aim of this study was to assess the association of Gal-3 with atrial fibrosis in patients with AF. This is a systematic review study. From the total number of studies analyzed, 12 demonstrated a relation between atrial fibrosis and Gal-3 in patients with AF and presented statistically significant association values. We conclude that Gal-3 is associated with atrial fibrosis in patients with AF in all types, as well as after the arrhythmia treatment by ablation.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Prognostic_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Prognostic_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article