Vaccinia Virus Immunomodulator A46: Destructive Interactions with MAL and MyD88 Shown by Negative-Stain Electron Microscopy.

Azar, Daniel F; Haas, Meryl; Fedosyuk, Sofiya; Rahaman, Md Habibur; Hedger, Andrew; Kobe, Bostjan; Skern, Tim

Azar, Daniel F; Haas, Meryl; Fedosyuk, Sofiya; Rahaman, Md Habibur; Hedger, Andrew; Kobe, Bostjan; Skern, Tim.

Afiliação

Azar DF; Max Perutz Labs, Medical University of Vienna, Vienna Biocenter, Dr. Bohr-Gasse 9/3, 1030 Vienna, Austria.
Haas M; Max Perutz Labs, Medical University of Vienna, Vienna Biocenter, Dr. Bohr-Gasse 9/3, 1030 Vienna, Austria.
Fedosyuk S; Max Perutz Labs, Medical University of Vienna, Vienna Biocenter, Dr. Bohr-Gasse 9/3, 1030 Vienna, Austria; Jenner Institute, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
Rahaman MH; School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia.
Hedger A; School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia.
Kobe B; School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia.
Skern T; Max Perutz Labs, Medical University of Vienna, Vienna Biocenter, Dr. Bohr-Gasse 9/3, 1030 Vienna, Austria. Electronic address: timothy.skern@meduniwien.ac.at.

Structure ; 28(12): 1271-1287.e5, 2020 12 01.

Article em En | MEDLINE | ID: mdl-33035450

Assuntos

Proteínas Proteolipídicas Associadas a Linfócitos e Mielina/química; Fator 88 de Diferenciação Mieloide/química; Proteínas Virais/química; Sítios de Ligação; Humanos; Microscopia Eletrônica; Simulação de Acoplamento Molecular; Mutagênese; Proteínas Proteolipídicas Associadas a Linfócitos e Mielina/metabolismo; Fator 88 de Diferenciação Mieloide/metabolismo; Ligação Proteica; Proteínas Virais/genética; Proteínas Virais/metabolismo

Palavras-chave

Bcl-2 family proteins; MyD88 signalosome; Toll-like receptors; cooperative assembly formation; inflammation; protein cross-linking; protein-protein interactions; viral immunology; viral immunomodulators

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Virais / Fator 88 de Diferenciação Mieloide / Proteínas Proteolipídicas Associadas a Linfócitos e Mielina Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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