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Immunopathological features of air pollution and its impact on inflammatory airway diseases (IAD).
Rouadi, Philip W; Idriss, Samar A; Naclerio, Robert M; Peden, David B; Ansotegui, Ignacio J; Canonica, Giorgio Walter; Gonzalez-Diaz, Sandra Nora; Rosario Filho, Nelson A; Ivancevich, Juan Carlos; Hellings, Peter W; Murrieta-Aguttes, Margarita; Zaitoun, Fares H; Irani, Carla; Karam, Marilyn R; Bousquet, Jean.
Afiliação
  • Rouadi PW; Department of Otolaryngology-Head and Neck Surgery, Eye and Ear University Hospital, Beirut, Lebanon.
  • Idriss SA; Department of Otolaryngology-Head and Neck Surgery, Eye and Ear University Hospital, Beirut, Lebanon.
  • Naclerio RM; Johns Hopkins University Department of Otolaryngology - Head and Neck Surgery, Baltimore, MD, USA.
  • Peden DB; UNC Center for Environmental Medicine, Asthma, and Lung Biology, Division of Allergy, Immunology and Rheumatology, Department of Pediatrics UNS School of Medicine, USA.
  • Ansotegui IJ; Department of Allergy and Immunology, Hospital Quironsalud Bizkaia, Bilbao, Spain.
  • Canonica GW; Asthma & Allergy Clinic,Humanitas University & Research Hospital IRCCS, Milano, Italy.
  • Gonzalez-Diaz SN; University Autonoma de Nuevo Leon Facultad de Medicina y Hospital Universitario U.A.N.L, Monterrey, NL, c.p. 64460, México.
  • Rosario Filho NA; Federal University of Parana, Brazil.
  • Ivancevich JC; Faculty of Medicine, Universidad del Salvador, Buenos Aires, Argentina and Head of Allergy and Immunology at the Santa Isabel Clinic, Buenos Aires, Argentina.
  • Hellings PW; Department of Otorhinolaryngology, University Hospitals Leuven, Leuven, Belgium.
  • Murrieta-Aguttes M; Department of Otorhinolaryngology, Academic Medical Center Amsterdam, The Netherlands - Department Otorhinolaryngology, University Hospital Ghent, Belgium.
  • Zaitoun FH; 8 Rue Pierre Poli, Issy Les Moulineaux, 92130, France.
  • Irani C; LAUMC Rizk Hospital, Otolaryngology-Allergy Department, Beirut, Lebanon.
  • Karam MR; Department of Internal Medicine and Infectious Diseases, St Joseph University, Hotel Dieu de France Hospital, Beirut, Lebanon.
  • Bousquet J; Division of Rheumatology, Allergy and Clinical Immunology, Department of Internal Medicine, American University of Beirut, Beirut, Lebanon.
World Allergy Organ J ; 13(10): 100467, 2020 Oct.
Article em En | MEDLINE | ID: mdl-33042360
ABSTRACT
Air pollution causes significant morbidity and mortality in patients with inflammatory airway diseases (IAD) such as allergic rhinitis (AR), chronic rhinosinusitis (CRS), asthma, and chronic obstructive pulmonary disease (COPD). Oxidative stress in patients with IAD can induce eosinophilic inflammation in the airways, augment atopic allergic sensitization, and increase susceptibility to infection. We reviewed emerging data depicting the involvement of oxidative stress in IAD patients. We evaluated biomarkers, outcome measures and immunopathological alterations across the airway mucosal barrier following exposure, particularly when accentuated by an infectious insult.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article