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Four new triterpene glucosides from Salacia cochinchinensis Lour.
Gao, Lu; Duan, Li-Kun; Feng, Jin-E; Jiang, Yun-Tao; Gao, Jun; Fan, Jun-Ting; Dai, Rong; Jiang, Zhi-Yong.
Afiliação
  • Gao L; Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan Minzu University, Kunming, Yunnan, China.
  • Duan LK; Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan Minzu University, Kunming, Yunnan, China.
  • Feng JE; Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan Minzu University, Kunming, Yunnan, China.
  • Jiang YT; Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan Minzu University, Kunming, Yunnan, China.
  • Gao J; Nanjing Institute of Environmental Sciences, Ministry of Ecology and Environment of the People's Republic of China, Nanjing, China.
  • Fan JT; Department of Pharmceutical Analysis, School of Pharmacy, Nanjing Medical University, Nanjing, China.
  • Dai R; Nanjing Institute of Environmental Sciences, Ministry of Ecology and Environment of the People's Republic of China, Nanjing, China.
  • Jiang ZY; State Environmental Protection Key Laboratory of Biosafety, Ministry of Ecology and Environment of China, Nanjing, China.
Nat Prod Res ; 36(9): 2292-2299, 2022 May.
Article em En | MEDLINE | ID: mdl-33043693
Four new triterpene glucosides (1-4) were isolated from the 90% ethanol extract of Salacia cochinchinensis, together with five known compounds (5-9). The structures of the new compounds were elucidated by comprehensive spectroscopic analysis including HRESIMS, IR, 1 D and 2 D NMR analysis. All isolates were assayed for their α-glucosidase inhibitory activity. Compound 9 showed remarkable α-glucosidase inhibitory activity with an IC50 value of 0.31 µM, and the triterpene glycosides (1-5) exhibited moderate α-glucosidase inhibitory activity.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triterpenos / Salacia Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triterpenos / Salacia Idioma: En Ano de publicação: 2022 Tipo de documento: Article