Balancing the Opposing Principles That Govern Peroxisome Homeostasis.
Trends Biochem Sci
; 46(3): 200-212, 2021 03.
Article
em En
| MEDLINE
| ID: mdl-33046344
ABSTRACT
Despite major advances in our understanding of players and mechanisms involved in peroxisome biogenesis and peroxisome degradation, very few studies have focused on unraveling the multi-layered connections between, and the coordination of, these two opposing processes that regulate peroxisome homeostasis. The intersection between these processes also provides exciting avenues for future research. This review highlights the links between peroxisome biogenesis and degradation, incorporating an integrative approach that is critical not only for a mechanistic understanding, but also for manipulating the balance between these processes in relevant disease models.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Peroxissomos
/
Redes e Vias Metabólicas
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article