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Synthesis, binding, and functional properties of tetrahydroisoquinolino-2-alkyl phenones as selective σ2R/TMEM97 ligands.
Xie, Xiao-Yang; Li, Yu-Yun; Ma, Wen-Hui; Chen, Ai-Fang; Sun, Yu-Tong; Lee, Ji Youn; Riad, Aladdin; Xu, Dao-Hua; Mach, Robert H; Huang, Yun-Sheng.
Afiliação
  • Xie XY; School of Pharmacy, Guangdong Medical University, 1 Xincheng Ave, Songshan Lake Technology Park, Dongguan, Guangdong 523808, China.
  • Li YY; School of Pharmacy, Guangdong Medical University, 1 Xincheng Ave, Songshan Lake Technology Park, Dongguan, Guangdong 523808, China.
  • Ma WH; School of Pharmacy, Guangdong Medical University, 1 Xincheng Ave, Songshan Lake Technology Park, Dongguan, Guangdong 523808, China.
  • Chen AF; School of Pharmacy, Guangdong Medical University, 1 Xincheng Ave, Songshan Lake Technology Park, Dongguan, Guangdong 523808, China.
  • Sun YT; School of Pharmacy, Guangdong Medical University, 1 Xincheng Ave, Songshan Lake Technology Park, Dongguan, Guangdong 523808, China.
  • Lee JY; Department of Radiology, University of Pennsylvania, 231 S. 34th St, Philadelphia, PA, 19104, USA.
  • Riad A; Department of Radiology, University of Pennsylvania, 231 S. 34th St, Philadelphia, PA, 19104, USA.
  • Xu DH; School of Pharmacy, Guangdong Medical University, 1 Xincheng Ave, Songshan Lake Technology Park, Dongguan, Guangdong 523808, China.
  • Mach RH; Department of Radiology, University of Pennsylvania, 231 S. 34th St, Philadelphia, PA, 19104, USA. Electronic address: rmach@mail.med.upenn.edu.
  • Huang YS; School of Pharmacy, Guangdong Medical University, 1 Xincheng Ave, Songshan Lake Technology Park, Dongguan, Guangdong 523808, China. Electronic address: yshuang@gdmu.edu.cn.
Eur J Med Chem ; 209: 112906, 2021 Jan 01.
Article em En | MEDLINE | ID: mdl-33049607
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores sigma / Fármacos Neuroprotetores / Doenças Neurodegenerativas / Tetra-Hidroisoquinolinas / Proteínas de Membrana Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores sigma / Fármacos Neuroprotetores / Doenças Neurodegenerativas / Tetra-Hidroisoquinolinas / Proteínas de Membrana Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article