p50 suppresses cytotoxic T lymphocyte effector function to regulate tumor immune escape and response to immunotherapy.

Lu, Chunwan; Klement, John D; Smith, Alyssa D; Yang, Dafeng; Waller, Jennifer L; Browning, Darren D; Munn, David H; Liu, Kebin

Lu, Chunwan; Klement, John D; Smith, Alyssa D; Yang, Dafeng; Waller, Jennifer L; Browning, Darren D; Munn, David H; Liu, Kebin.

Afiliação

Lu C; Department of Biochemistry and Molecular Biology, Augusta University, Augusta, Georgia, United States Clu@augusta.edu kliu@augusta.edu.
Klement JD; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia, United States.
Smith AD; Charlie Norwood VA Medical Center, Augusta, Georgia, United States.
Yang D; Department of Biochemistry and Molecular Biology, Augusta University, Augusta, Georgia, United States.
Waller JL; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia, United States.
Browning DD; Charlie Norwood VA Medical Center, Augusta, Georgia, United States.
Munn DH; Department of Biochemistry and Molecular Biology, Augusta University, Augusta, Georgia, United States.
Liu K; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia, United States.

J Immunother Cancer ; 8(2)2020 10.

Article em En | MEDLINE | ID: mdl-33051343

Assuntos

Imunoterapia/métodos; Linfócitos T Citotóxicos/imunologia; Animais; Modelos Animais de Doenças; Feminino; Humanos; Camundongos; Evasão Tumoral

Palavras-chave

CD8-positive T-lymphocytes; gastrointestinal neoplasms; immune evation; immunotherapy; inflammation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T Citotóxicos / Imunoterapia Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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