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Immortalization of human hepatocytes from biliary atresia with CDK4R24C, cyclin D1, and TERT for cytochrome P450 induction testing.
Nishiwaki, Manami; Toyoda, Masashi; Oishi, Yoshie; Ishida, Seiichi; Horiuchi, Shin-Ichiro; Makino-Itou, Hatsune; Kimura, Tohru; Ohno, Shin-Ichi; Ohkura, Takashi; Enosawa, Shin; Akutsu, Hidenori; Nakazawa, Atsuko; Kasahara, Mureo; Kiyono, Tohru; Umezawa, Akihiro.
Afiliação
  • Nishiwaki M; Center for Regenerative Medicine, National Center for Child Health and Development Research Institute, Tokyo, 157-8535, Japan.
  • Toyoda M; Center for Regenerative Medicine, National Center for Child Health and Development Research Institute, Tokyo, 157-8535, Japan.
  • Oishi Y; Research Team for Geriatric Medicine (Vascular Medicine), Tokyo Metropolitan Institute of Gerontology, Tokyo, 173-0015, Japan.
  • Ishida S; Center for Regenerative Medicine, National Center for Child Health and Development Research Institute, Tokyo, 157-8535, Japan.
  • Horiuchi SI; Division of Pharmacology, National Institute of Health Sciences, Kanagawa, 210-9501, Japan.
  • Makino-Itou H; Division of Pharmacology, National Institute of Health Sciences, Kanagawa, 210-9501, Japan.
  • Kimura T; Center for Regenerative Medicine, National Center for Child Health and Development Research Institute, Tokyo, 157-8535, Japan.
  • Ohno SI; Laboratory of Stem Cell Biology, Department of Biosciences, Kitasato University School of Science, Kanagawa, 252-0373, Japan.
  • Ohkura T; Center for Regenerative Medicine, National Center for Child Health and Development Research Institute, Tokyo, 157-8535, Japan.
  • Enosawa S; Center for Regenerative Medicine, National Center for Child Health and Development Research Institute, Tokyo, 157-8535, Japan.
  • Akutsu H; Division for Advanced Medical Sciences, National Center for Child Health and Development, Tokyo, 157-8535, Japan.
  • Nakazawa A; Center for Regenerative Medicine, National Center for Child Health and Development Research Institute, Tokyo, 157-8535, Japan.
  • Kasahara M; Center for Regenerative Medicine, National Center for Child Health and Development Research Institute, Tokyo, 157-8535, Japan.
  • Kiyono T; Saitama Children's Medical Center, Saitama, 330-8777, Japan.
  • Umezawa A; Organ Transplantation Center, National Center for Child Health and Development, Tokyo, 157-8535, Japan.
Sci Rep ; 10(1): 17503, 2020 10 15.
Article em En | MEDLINE | ID: mdl-33060611

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Atresia Biliar / Telomerase / Técnicas de Cultura de Células / Fígado Artificial / Ciclina D1 / Hepatócitos / Quinase 4 Dependente de Ciclina Limite: Child, preschool / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Atresia Biliar / Telomerase / Técnicas de Cultura de Células / Fígado Artificial / Ciclina D1 / Hepatócitos / Quinase 4 Dependente de Ciclina Limite: Child, preschool / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article