Risk Factor Profiles Can Distinguish Esophageal Adenocarcinoma From Barrett's Esophagus.
Am J Gastroenterol
; 116(1): 198-201, 2021 01 01.
Article
em En
| MEDLINE
| ID: mdl-33065588
ABSTRACT
INTRODUCTION:
It is assumed that screening risk factors for Barrett's esophagus (BE) and prevalent esophageal adenocarcinoma (EAC) are the same.METHODS:
A matched case-control study comparing risk factors between EAC and BE was performed.RESULTS:
In 1,356 patients (678 with EAC and 678 with BE), heartburn (52.7%), diabetes, hyperlipidemia, hypertension, nonalcoholic steatohepatitis, and metabolic syndrome were less common in EAC (52.7, 29.2, 45.7, 48.2, 12, and 28.5%, resp.) compared with BE (84.5, 37.6, 82.2, 64.6, 18.4, and 44.1%, P < 0.01). Mean alanine aminotransferase and HgA1c levels were also significantly lower in EAC compared with BE.DISCUSSION:
Optimal strategies for screening for prevalent EAC may be different than that for BE.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Esôfago de Barrett
/
Neoplasias Esofágicas
/
Adenocarcinoma
/
Refluxo Gastroesofágico
/
Síndrome Metabólica
/
Diabetes Mellitus
/
Azia
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
/
Screening_studies
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article