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Targeting antioxidant enzymes enhances the therapeutic efficacy of the BCL-XL inhibitor ABT-263 in KRAS-mutant colorectal cancers.
Oh, Yumi; Jung, Hae Rim; Min, Seoyeon; Kang, Jinjoo; Jang, Dongjun; Shin, Seungjae; Kim, Jiwon; Lee, Sang Eun; Sung, Chang Ohk; Lee, Won-Suk; Lee, Charles; Jeong, Eui Man; Cho, Sung-Yup.
Afiliação
  • Oh Y; Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea; Medical Research Center, Genomic Medicine Institute (GMI), Seoul National University College of Medicine, Seoul, 03080, Korea.
  • Jung HR; Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea; Medical Research Center, Genomic Medicine Institute (GMI), Seoul National University College of Medicine, Seoul, 03080, Korea.
  • Min S; Department of Life Science, Ewha Womans University, Seoul, 03760, Republic of Korea.
  • Kang J; Department of Life Science, Ewha Womans University, Seoul, 03760, Republic of Korea.
  • Jang D; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.
  • Shin S; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.
  • Kim J; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.
  • Lee SE; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.
  • Sung CO; Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, 05505, Republic of Korea.
  • Lee WS; Department of Surgery, Gil Medical Center, Gachon University, Incheon, 21565, Republic of Korea.
  • Lee C; Department of Life Science, Ewha Womans University, Seoul, 03760, Republic of Korea; The Jackson Laboratory for Genomic Medicine, Farmington, CT, 06032, USA.
  • Jeong EM; Department of Pharmacy, College of Pharmacy, Jeju National University, Jeju Special Self-Governing Province, 63243, Republic of Korea; Interdisciplinary Graduate Program in Advanced Convergence Technology and Science, Jeju National University, Jeju Special Self-Governing Province, 63243, Republic of
  • Cho SY; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea; Cancer Research Institute, Seoul National University, Seoul, 03080, Republic of Korea; Medical Research Center, Genomic Medicine Institute (GMI), Seoul National University College of Me
Cancer Lett ; 497: 123-136, 2021 01 28.
Article em En | MEDLINE | ID: mdl-33068701
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Neoplasias Colorretais / Biomarcadores Tumorais / Proteínas Proto-Oncogênicas p21(ras) / Proteína bcl-X / Compostos de Anilina / Mutação / Antioxidantes Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Neoplasias Colorretais / Biomarcadores Tumorais / Proteínas Proto-Oncogênicas p21(ras) / Proteína bcl-X / Compostos de Anilina / Mutação / Antioxidantes Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article