Quality of evidence of the efficacy of therapeutic interventions on patient-important outcomes in Cochrane's systematic reviews' abstracts: A survey.
Therapie
; : 403-408, 2020 Sep 28.
Article
em En
| MEDLINE
| ID: mdl-33077183
ABSTRACT
OBJECTIVE:
The objective of this study was to evaluate the proportion of therapeutics that have proven their efficacy on patient-important outcomes with a high quality of evidence among Cochrane systematic reviews (SRs).METHODS:
We surveyed a random sample of 400 SRs' abstracts published between September 2012 and December 2015, which compared therapeutic interventions with at least a placebo or no intervention control. The primary endpoint was the proportion of SRs with a statistically significant efficacy on a patient-important outcome and with a high quality of evidence.RESULTS:
Among the 400 abstracts surveyed, 32 (8%) found efficacy on a patient-important outcome with a high quality of evidence. Half of the 400 SRs (50.2%) evaluated a pharmacological intervention and 12% of these found efficacy of the intervention on a patient-important outcome with a reported high quality of evidence.CONCLUSION:
Based on an analysis of 400 abstracts of SRs from the Cochrane Collaboration, we found that there is a low number of therapeutic interventions which have proven their efficacy on patient-important outcomes with a high quality of evidence.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Clinical_trials
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article