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Preclinical in vitro and in vivo pharmacokinetic properties of danicamtiv, a new targeted myosin activator for the treatment of dilated cardiomyopathy.
Grillo, Mark P; Markova, Svetlana; Evanchik, Marc; Trellu, Marc; Moliner, Patricia; Brun, Priscilla; Perreard-Dumaine, Anne; Vicat, Pascale; Driscoll, James P; Carlson, Tim J.
Afiliação
  • Grillo MP; Drug Metabolism and Pharmacokinetics, MyoKardia Inc, South San Francisco, CA, USA.
  • Markova S; Drug Metabolism and Pharmacokinetics, MyoKardia Inc, South San Francisco, CA, USA.
  • Evanchik M; Jazz Pharmaceuticals Inc, Palo Alto, CA, USA.
  • Trellu M; Drug Metabolism and Pharmacokinetics, MyoKardia Inc, South San Francisco, CA, USA.
  • Moliner P; Drug Metabolism and Pharmacokinetics, Assembly Biosciences Inc R&D Main Facility, South San Francisco, CA, USA.
  • Brun P; DMPK Research Platform France, Sanofi-Aventis Recherche et Développement, Chilly Mazarin, France.
  • Perreard-Dumaine A; Sanofi, Montpellier, France.
  • Vicat P; DMPK Research Platform France, Sanofi-Aventis Recherche et Développement, Chilly Mazarin, France.
  • Driscoll JP; DMPK Research Platform France, Sanofi-Aventis Recherche et Développement, Alfortville, France.
  • Carlson TJ; DMPK Research Platform France, Sanofi-Aventis Recherche et Développement, Alfortville, France.
Xenobiotica ; 51(2): 222-238, 2021 Feb.
Article em En | MEDLINE | ID: mdl-33078965
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cardiomiopatia Dilatada Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cardiomiopatia Dilatada Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article