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Influence of patient sex on the effectiveness of sacral neuromodulation: A cohort study from China.
Meng, Lingfeng; Tian, Zijian; Zhang, Wei; Zhang, Yaoguang; Wang, Jianye; Liao, Limin; Ling, Qing; Zhang, Peng; Wei, Zhongqing; Zhong, Tie; Xu, Zhihui; Wen, Wei; Li, Jiayi; Luo, Deyi.
Afiliação
  • Meng L; Department of Urology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, 100730, China.
  • Tian Z; Department of Urology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, 100730, China.
  • Zhang W; Department of Urology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, 100730, China.
  • Zhang Y; Department of Urology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, 100730, China. Electronic address: zhang003887@sina.com.
  • Wang J; Department of Urology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, 100730, China.
  • Liao L; Department of Urology, China Rehabilitation Research Centre, Rehabilitation School of Capital Medical University, Beijing, 100068, China.
  • Ling Q; Department of Urology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, 430030, China.
  • Zhang P; Department of Urology, Beijing Chaoyang Hospital, Institute of Urology, Capital Medical University, Beijing, 100020, China.
  • Wei Z; Department of Urology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, 210000, China.
  • Zhong T; Department of Urology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710014, China.
  • Xu Z; Department of Urology, Zhejiang Provincial People's Hospital, Hangzhou, 310000, China.
  • Wen W; Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200000, China.
  • Li J; Department of Urology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200000, China.
  • Luo D; Department of Urology, West China Hospital, Sichuan University, Chengdu, 610000, China.
Int J Surg ; 84: 13-17, 2020 Dec.
Article em En | MEDLINE | ID: mdl-33080412
BACKGROUND: Sacral neuromodulation (SNM) has been widely used to treat lower urinary tract dysfunction. Studies have shown a higher conversion rate among female patients than among male patients. However, the influence of gender on the clinical effectiveness of SNM remains unclear. We aimed to confirm whether patients of both genders show similar benefits after SNM treatment. MATERIALS AND METHODS: Clinical data of patients with lower urinary tract symptoms associated with pelvic floor dysfunction (overactive bladder, neurogenic bladder, interstitial cystitis/painful bladder syndrome, idiopathic urinary retention) treated with SNM in 10 medical centres in China between January 2012 and December 2016 were retrospectively collected. The patients were classified by gender. Variations in objective (voiding diary) and subjective scores in the baseline, testing, and last follow-up periods were compared. Data were analysed using statistical measures. RESULTS: The study included 203 patients (93 males, 110 females). There were no statistical differences in baseline information between the two groups, both groups showed improvement over time. Unsatisfactory improvement was observed in the quality of life and sexual life scores of both groups over the entire treatment period (all p>0.05). Although there was a difference in the maximum voiding volume between the groups at baseline, no difference was observed at the last follow-up (p = 0.004, p = 0.044, p = 0.124), unlike in the average volume where a difference was noted at the last follow-up (p = 0.085, p = 0.964, p = 0.031). While there were no differences in quality of life, sexual life, or pelvic pain and urinary urgency frequency scores at baseline, a significant difference was observed at the last follow-up, and the degree of improvement was less among female patients (p = 0.836, p = 0.131, p = 0.015; p = 0.294, p = 0.265, p = 0.013; p = 0.299, p = 0.087, p = 0.015). CONCLUSION: SNM treatment elicited a similar effect on patients of both gender; however, a significant difference was observed regarding patient satisfaction with the treatment. Further preoperative patient education, especially, for female patients with interstitial cystitis/painful bladder syndrome may improve patient satisfaction.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Terapia por Estimulação Elétrica / Sintomas do Trato Urinário Inferior Tipo de estudo: Etiology_studies / Observational_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Terapia por Estimulação Elétrica / Sintomas do Trato Urinário Inferior Tipo de estudo: Etiology_studies / Observational_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article