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Inhaled corticosteroids and the risk of type 2 diabetes among Swedish COPD patients.
Ställberg, Björn; Janson, Christer; Lisspers, Karin; Johansson, Gunnar; Gutzwiller, Florian S; Mezzi, Karen; Bjerregaard, Bine Kjoeller; Kejs, Anne Mette Tranberg; Jorgensen, Leif; Larsson, Kjell.
Afiliação
  • Ställberg B; Department of Public Health and Caring Sciences, Family Medicine and Preventive Medicine, Uppsala University, Uppsala, Sweden. b.stallberg@telia.com.
  • Janson C; Department of Medical Sciences: Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden.
  • Lisspers K; Department of Public Health and Caring Sciences, Family Medicine and Preventive Medicine, Uppsala University, Uppsala, Sweden.
  • Johansson G; Department of Public Health and Caring Sciences, Family Medicine and Preventive Medicine, Uppsala University, Uppsala, Sweden.
  • Gutzwiller FS; Novartis Pharma AG, Basel, Switzerland.
  • Mezzi K; Novartis Pharma AG, Basel, Switzerland.
  • Bjerregaard BK; IQVIA Solutions, Copenhagen, Denmark.
  • Kejs AMT; IQVIA Solutions, Copenhagen, Denmark.
  • Jorgensen L; IQVIA Solutions, Copenhagen, Denmark.
  • Larsson K; Integrative Toxicology, The National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
NPJ Prim Care Respir Med ; 30(1): 47, 2020 10 20.
Article em En | MEDLINE | ID: mdl-33082331
ABSTRACT
This study reports the association of ICS use and the risk of type 2 diabetes mellitus (T2DM) in Swedish patients with COPD using data from real-world, primary care settings. A total of 7078 patients with COPD were included in this analysis and the 5-year cumulative incidence rate per 100,000 person years was 1506.9. The yearly incidence rate per 100,000 person years ranged from 850 to 1919. Use of ICS especially at a high dose in patients with COPD was related to an increased risk of T2DM.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Broncodilatadores / Corticosteroides / Doença Pulmonar Obstrutiva Crônica / Diabetes Mellitus Tipo 2 Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male País/Região como assunto: Europa Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Broncodilatadores / Corticosteroides / Doença Pulmonar Obstrutiva Crônica / Diabetes Mellitus Tipo 2 Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male País/Região como assunto: Europa Idioma: En Ano de publicação: 2020 Tipo de documento: Article