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Cell-Type Transcriptome Atlas of Human Aortic Valves Reveal Cell Heterogeneity and Endothelial to Mesenchymal Transition Involved in Calcific Aortic Valve Disease.
Xu, Kang; Xie, Shangbo; Huang, Yuming; Zhou, Tingwen; Liu, Ming; Zhu, Peng; Wang, Chunli; Shi, Jiawei; Li, Fei; Sellke, Frank W; Dong, Nianguo.
Afiliação
  • Xu K; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (K.X., Y.H., T.Z., M.L., P.Z., J.S., F.L., N.D.).
  • Xie S; BGI-Tech, BGI-Shenzhen, Guangdong, China (S.X.).
  • Huang Y; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (K.X., Y.H., T.Z., M.L., P.Z., J.S., F.L., N.D.).
  • Zhou T; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (K.X., Y.H., T.Z., M.L., P.Z., J.S., F.L., N.D.).
  • Liu M; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (K.X., Y.H., T.Z., M.L., P.Z., J.S., F.L., N.D.).
  • Zhu P; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (K.X., Y.H., T.Z., M.L., P.Z., J.S., F.L., N.D.).
  • Wang C; National Innovation and Attracting Talents "111" base, Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, China (C.W.).
  • Shi J; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (K.X., Y.H., T.Z., M.L., P.Z., J.S., F.L., N.D.).
  • Li F; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (K.X., Y.H., T.Z., M.L., P.Z., J.S., F.L., N.D.).
  • Sellke FW; Division of Cardiothoracic Surgery, Department of Surgery, Cardiovascular Research Center, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, RI (F.W.S.).
  • Dong N; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (K.X., Y.H., T.Z., M.L., P.Z., J.S., F.L., N.D.).
Arterioscler Thromb Vasc Biol ; 40(12): 2910-2921, 2020 12.
Article em En | MEDLINE | ID: mdl-33086873

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Valva Aórtica / Calcinose / Células Endoteliais / Redes Reguladoras de Genes / Transição Epitelial-Mesenquimal / Transcriptoma / Doenças das Valvas Cardíacas Tipo de estudo: Observational_studies / Prognostic_studies Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Valva Aórtica / Calcinose / Células Endoteliais / Redes Reguladoras de Genes / Transição Epitelial-Mesenquimal / Transcriptoma / Doenças das Valvas Cardíacas Tipo de estudo: Observational_studies / Prognostic_studies Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article