MicroRNA-206, IL-4, IL-13, and INF-Î³ levels in lung tissue and plasma are increased by the stimulation of particulate matter with a diameter of &#8804;2.5µm, and are associated with the poor prognosis of asthma induced pulmonary arterial hypertension patients.

Li, Shaohua; Ma, Xiaoning; Xie, Jianli; Yan, Xixin; Sun, Wuzhuang

MicroRNA-206, IL-4, IL-13, and INF-Î³ levels in lung tissue and plasma are increased by the stimulation of particulate matter with a diameter of ≤2.5µm, and are associated with the poor prognosis of asthma induced pulmonary arterial hypertension patients.

Li, Shaohua; Ma, Xiaoning; Xie, Jianli; Yan, Xixin; Sun, Wuzhuang.

Afiliação

Li S; Department of Respiratory and Critical Care Medical, The Second Hospital of Hebei Medical University , Shijiazhuang, Hebei, China.
Ma X; Department of Respiratory and Critical Care Medical, The First Hospital of Hebei Medical University , Shijiazhuang, Hebei, China.
Xie J; Intensive Care Unit of Shijiazhuang First Hospital, People's Hospital in Shijiazhuang , Shijiazhuang, Hebei, China.
Yan X; Rheumatology and Immunology Department, The Third Hospital of Hebei Medical University , Shijiazhuang, Hebei, China.
Sun W; Department of Respiratory and Critical Care Medical, The Second Hospital of Hebei Medical University , Shijiazhuang, Hebei, China.

Clin Exp Hypertens ; 43(2): 181-188, 2021 Feb 17.

Article em En | MEDLINE | ID: mdl-33086901

Assuntos

Asma; Interferon gama; Interleucina-13; Interleucina-4; Pulmão/metabolismo; MicroRNAs; Material Particulado; Hipertensão Arterial Pulmonar; Animais; Asma/complicações; Asma/metabolismo; Feminino; Perfilação da Expressão Gênica; Humanos; Interferon gama/análise; Interferon gama/sangue; Interleucina-13/análise; Interleucina-13/sangue; Interleucina-4/análise; Interleucina-4/sangue; Masculino; Camundongos; Camundongos Endogâmicos BALB C; MicroRNAs/análise; MicroRNAs/sangue; Pessoa de Meia-Idade; Material Particulado/efeitos adversos; Material Particulado/análise; Prognóstico; Hipertensão Arterial Pulmonar/diagnóstico; Hipertensão Arterial Pulmonar/etiologia; Hipertensão Arterial Pulmonar/metabolismo

Palavras-chave

PM2.5; Pulmonary arterial hypertension; asthma; inflammatory; prognosis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Asma / Interleucina-4 / Interferon gama / Interleucina-13 / MicroRNAs / Material Particulado / Hipertensão Arterial Pulmonar / Pulmão Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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